FBISE Biology Guess Paper 2026 HSSC-I (1st Year) | Federal Board Biology Important Topics

⭐ HSSC-I · Session 2025–2026

FBISE Biology Guess Paper 2026
Class 11 (1st Year)

Important topics from the National Book Foundation (NBF) Biology syllabus — covering 15 chapters with high-scoring concepts, definitions, and diagrams.

15Chapters

60+Topics

100%Free

FBISEFederal Board

Are you preparing for the FBISE Biology HSSC-I (1st Year) Annual Examinations 2026? This carefully prepared guess paper covers the most important topics from the National Book Foundation (NBF) Biology syllabus. It is designed to help students revise high-scoring concepts, important definitions, diagrams, and long questions before the board examination.

🧬 Chapter-Wise Important Topics

01 Cells and Sub-Cellular Organelles

• List of single and double membrane-bound organelles
• Ultra structure of animal and plant cells
• Golgi Complex, Plasma Membrane, Lysosomes, Endoplasmic Reticulum, Ribosomes and Nucleus
• Cell Signaling

02 Molecular Biology

• Amylase and Amylopectin
• Last 3–4 lines of all properties of water
• Structural conformation and classification of proteins
• Significance of amino acids
• Types of fatty acids
• Phospholipids, Steroids and Prostaglandins
• Watson and Crick Model of DNA

03 Enzymes

• Types of Cofactors
• Enzyme Inhibition
• Definitions of Ribozyme, Apoenzyme and Holoenzyme
• Effect of Temperature on Enzyme Activity
• Characteristics of Enzymes

04 Bioenergetics

• Photophosphorylation
• Glycolysis
• Krebs Cycle
• Calvin Cycle
• Electron Transport Chain (ETC)

05 Acellular Life

• Life Cycle of Bacteriophage
• Life Cycle of HIV
• Prions and Viroids
• Symptoms of AIDS

06 Prokaryotes

• Cyanobacteria
• Growth and Reproduction in Bacteria
• Definitions of Conjugation, Transduction and Transformation
• Physical and Chemical Methods to Control Bacteria
• Chemosynthetic Bacteria

07 Protista and Fungi

• Protista as a Polyphyletic Group
• Why Fungi are Classified as a Separate Kingdom
• Lichens and Mycorrhizae

08 Plantae

• Characteristics of Bryophytes
• Characteristics of Tracheophytes
• Angiosperms

09 Diversity in Plant Functions

• Opening and Closing of Stomata
• TACT Theory
• Thermoregulation in Plants
• Photoperiodism

10 Animalia

• Classification Based on Body Type
• Phylum Cnidaria
• Phylum Arthropoda
• Phylum Chordata
• Phylum Echinodermata

11 Reproduction

• Hormonal Control of Male Reproductive Function
• Female Reproductive Cycle and Hormonal Regulation

12 Inheritance

• Incomplete Dominance
• Epistasis
• Genetics of Haemophilia and Colour Blindness

13 Chromosome and DNA

• Griffith Experiment
• Mechanism of DNA Replication
• Characteristics of the Genetic Code and Protein Synthesis Practice
• Post-Transcriptional Modification
• Down Syndrome
• Sources and Types of Mutations

14 Evolution

• Endosymbiotic Theory
• Postulates and Limitations of Lamarckism and Darwinism
• Evidence of Evolution from Comparative Anatomy and Molecular Biology

15 Ecology

• Nitrogen Cycle
• Ecological Succession

📚 Preparation Tips

• Revise all important definitions and scientific terms.
• Practice diagrams of cells, organelles and DNA replication.
• Memorize biological cycles and life cycles.
• Prepare all textbook exercises and board-style short questions.
• Focus on conceptual understanding instead of rote learning.

Disclaimer: This guess paper is prepared for educational purposes based on important topics and previous examination trends. Students are advised to prepare the complete syllabus for the best performance in FBISE Annual Examinations 2026.