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Biology Guess Paper HSSC-I 2025

Are you preparing for the FBISE Biology HSSC-I (1st Year) exams in 2025? This carefully curated guess paper highlights the most important exercises and questions from the National Book Foundation syllabus to help you focus on high-yield topics and score better in your board exams.

📘 GUESS PAPER

Chapter 01: Cells and Sub-Cellular Organelles

  • Stem cells
  • Functions of ER, Golgi complex & Lysosome
  • Cell Signaling

Chapter 02: Molecular Biology

  • Last 3-4 lines of all properties of water
  • Structural Conformation in Protein
  • Significance of amino acid
  • Phospholipids and terpenes waxes
  • Ribonucleic Acid (RNA)

Chapter 03: Enzymes

  • Types of Cofactors
  • Enzyme Inhibition
  • Ribozyme, Apoenzyme, Holoenzyme (Definitions)
  • Characteristics of enzymes

Chapter 04: Bioenergetics

  • Photophosphorylation
  • Glycolysis
  • Calvin Cycle

Chapter 05: Acellular Life

  • Life cycle of Bacteriophage
  • Life cycle of HIV
  • Prions & Viroid
  • Symptoms of AIDs

Chapter 06: Prokaryotes

  • Cyanobacteria
  • Growth & Reproduction in Bacteria
  • Conjugation, Transduction & Transformation (Definitions)
  • Physical methods to control bacteria
  • Gram positive and Gram-negative Bacteria

Chapter 07: Protista and Fungi

  • Why are fungi classified as separate Kingdom?
  • Lichen & Mycorrhizae

Chapter 08: Plantae

  • Examples & common names of different groups of Seedless vascular plants
  • Difference between Dicot & Monocot
  • Life cycle of Angiosperms

Chapter 09: Diversity in Plant Functions

  • Translocation of Organic Solutes
  • Thermoregulation in Plants
  • Apical Dominance

Chapter 10: Animalia

  • Classification upon types of body
  • Phylum cnidaria
  • Phylum arthropoda 
  • Phylum chordata 
  • Class reptilia, mammalia, amphibia

Chapter 11: Reproduction

  • Hormonal Control of Male Reproductive Function
  • Female Reproductive Cycle & its Hormonal Regulation

Chapter 12: Inheritance

  • Epistasis
  • Genetics of Haemophilia & Color blindness

Chapter 13: Chromosome and DNA

  • Mechanism of DNA Replication
  • Characteristics of Genetic code
  • Post transcriptional Modification
  • Down Syndrome

Chapter 14: Evolution

  • Endosymbiosis Theory
  • Postulates & examples of Lamarckism & Darwinism
  • Evidence of Evolution from Comparative Anatomy

Chapter 15: Ecology

  •  Nitrogen Cycle
  • Ecological Succession

🔬 Related Practical Activities for FBISE Biology

🧪 Bonus Practical Links (Physics & General Science)

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